The University of Alaska Fairbanks (UAF or Alaska) is a public land-grant research university in College, Alaska, a suburb of Fairbanks. It is the flagship campus of the University of Alaska system. UAF was established in 1917 and opened for classes in 1922. Originally named the Alaska Agricultural College and School of Mines, it became the University of Alaska in 1935. Fairbanks-based programs became the University of Alaska Fairbanks in 1975.

UAF is classified among "R2: Doctoral Universities – High research activity." It is home to several major research units, including the Agricultural and Forestry Experiment Station; the Geophysical Institute, which operates the Poker Flat Research Range and several other scientific centers; the Alaska Center for Energy and Power; the International Arctic Research Center; the Institute of Arctic Biology; the Institute of Marine Science; and the Institute of Northern Engineering. Located just 200 miles (320 km) south of the Arctic Circle, the Fairbanks campus' unique location favors Arctic and northern research. UAF's research specialties are renowned worldwide, most notably Arctic biology, Arctic engineering, geophysics, supercomputing, ethnobotany, and Alaska Native studies. The University of Alaska Museum of the North is also on the Fairbanks campus.

In addition to the Fairbanks campus, UAF encompasses six rural and urban campuses: Bristol Bay Campus in Dillingham; Chukchi Campus in Kotzebue; the Fairbanks-based Interior Alaska Campus, which serves the state's rural Interior; Kuskokwim Campus in Bethel; Northwest Campus in Nome; and the UAF Community and Technical College, with headquarters in downtown Fairbanks. UAF is also the home of UAF eCampus, which offers fully online programs.

In fall 2017, UAF enrolled 8,720 students. Of those students, 58% were female and 41% were male; 87.8% were undergraduates, and 12.2% were graduate students. As of May 2018, 1,352 students had graduated during the immediately preceding summer, fall, and spring semesters.